Tuesday, September 24, 2013

Introduction to Bioinformatics - part 2

If you have not read my first post about Bioinformatics Read it first.

Bioinformatics mainly refers to manipulate and analyzing biological data. These data cannot analyze or manipulate manually by human. So these data should store in computation databases, mainly in relational databases. So queries and other advanced algorithms can be used to analyze and interpret these data.

Bioinformatics databases can be categorized in many ways according different criteria.
These databases can be vary from Nature of information stored and Manner of information stored.


Categories of Bioinformatics databases.

Primary databases

Store sequences in central repositories and mainly lie into 2 parts.

  1. Nucleic Acid Databases ( Nucleotide Sequences )
  2. Protein Databases ( Amino Acid Sequences )
Secondary Databases

Contains results of analysis of the sequences in the primary sources. 
Ex: Pattern Databases, Refseq

Let's talk about Nucleic Acid Sequence Databases in Primary databases category.

Mainly there are 3 Nucleic Acid Sequence Databases have maintained in different facilities in the world. But today they all connected together to retrieve information in a better way.

  • EMBL - European Molecular Biology Laboratory., UK
  • GenBank - National Center for Biotechnology Information ( NCBI ) ,USA
  • DDBJ - DNA Data Bank of Japan



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